ABSTRACT
Objective To discuss the application value of ultrasound and shear wave elastography in the diagnosis of breast cancer.Methods From February 2014 to February 2016,61 patients with non palpable breast cancer in the First People's Hospital of Linhai were selected in this research.The patients were examined by conven-tional ultrasound( control group ),ultrasound shear wave elastography ( observation group ).The diagnosis accuracy, sensitivity,specificity were compared between the two groups.Results The diagnosis accuracy ,sensitivity,specificity of the observation group were 96.7%,96.2%,100.0%,respectively,which were significantly higher than those of the control group (78.7%,75.0%,64.7%),and the differences were statistically significant (χ2＝9.2,9.1,4.2,all P＜0.05).Conclusion Ultrasound and shear wave elastography in the diagnosis of non palpable breast cancer has better diagnostic value , the nature of disease with higher diagnostic accuracy ,high sensitivity and identification of cancerous lesions,better specificity,early diagnosis is helpful to the disease and treatment of patients with broken , meet the expectations.
ABSTRACT
BACKGROUND:Papain-induced rat knee osteoarthritis is a common modeling method, which can obtain a stable osteoarthritis model. OBJECTIVE:To observe the change of ultrastructure of chondrocytes in the early process of papain-induced rat knee osteoarthritis under transmission electron microscope. METHODS:A total of 18 Sprague-Dawley rats were randomly divided into three groups. Two rats were considered as a normal control group, without intervention. The mixture of papain and L-cysteine was injected in right knee joint cavity of 16 rats to induce osteoarthritis models (osteoarthritis model group). Physiological saline was injected in the left side (physiological saline control group). At 1, 2, 4 and 6 weeks after injection, samples were col ected. Transmission electron microscope was used to observe the change of cartilage ultrastructure of the medial femoral condyle joint. RESULTS AND CONCLUSION:For the normal control group and physiological saline control group, their cytoplasm contained abundant rough endoplasmic reticulum and mitochondria. After 1 week of injection, mitochondria vacuoles and light expanded rough endoplasmic reticulum were visible. Two weeks later, lipid droplets appeared, mitochondria degeneration was distinct, vacuolization was serious and its number was reduced, and rough endoplasmic reticulum expansion was obvious. Four weeks later, lipid droplets became increased, and the number of mitochondria decreased significantly. Most of the rough endoplasmic reticula were highly expanded, and part of the rough endoplasmic reticula were dissolved and fractured. Six weeks later, a number of lipid droplets were visible in cytoplasm, most of the mitochondria disappeared, only a smal number of mitochondria existed, and most of the rough endoplasmic reticula were dissolved and fractured. These results confirmed that cartilage ultrastructure changes gradual y in the early process of papain-induced rat knee osteoarthritis under transmission electron microscope.
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Objective To investigate the diagnostic value of ultrasonic in cavernous transformation of the portal vein.Methods 12 patients with cavernous transformation of the portal vein which confirmed by CT and DSA were retrospectively analyzed.The ultrasonic features and the blood flow of portal vein were observed.Results Ultrasound showed portal vein stenosis and alveolar or network no resounding area around the portal vein.There was no blood flow or few flow signals in occlusive portal vein.The network around the portal vein filled with color blood flow signals.Conclusion Ultrasound was a no trauma and convenience method in the diagnosis of cavernous transformation of the portal vein.